Top Methylated Multivitamins for Kids
With our government still allowing folic acid to be put into food and supplements, informed parents know that they should be looking for a multivitamin not only without folic acid, but WITH good forms of folate and b12 that the body can actually use.
Unlike ordinary multis that rely on synthetic folic acid and cyanocobalamin (B12), methylated multivitamins use the active forms of nutrients like folinic acid/calcium folinate, methylfolate, methylcobalamin/adenosylcobalamin/hydroxocobalamin that the body can recognize and use right away. For children, this can make all the difference in energy, focus, mood, and long-term wellness.
But with so many brands on the market, which methylated multivitamin is best for kids? This guide will explain what to look for, compare some of the top brands, and show you why Vesica Wellness’s Children’s Methyl Multi Vite Chewable is a clear standout.
Medical Disclaimer: This article is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. The information provided here should not replace professional medical advice. Always consult with a qualified healthcare provider before starting or changing any supplement routine, especially for children.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Affiliate Disclosure: Some links in this article are affiliate links. If you use our links to make a purchase, it won’t cost you anything extra — but it does help support this work (and keeps us funded to keep producing content).
Top Methylated Multivitamins for Kids
Here’s a look at some of the most popular options on the market today — and how they stack up.
⭐ Vesica Wellness – Kid’s Methyl Multi Vite Chewable
For a kid’s multivitamin that includes methylated vitamins like methylfolate and methylcobalamin, Vesica Wellness’s comes in at the top of our list.
Folate: 100% DV (Daily Value) from Magnafolate® C (L-5-MTHF) – true methylfolate, the most bioavailable form for kids with MTHFR.
B12: 100% DV methylcobalamin – active form that supports nervous system health, red blood cell formation, and steady energy.
Other Active B’s: Includes P5P (B6), riboflavin-5’-phosphate (B2), niacinamide, biotin, pantothenic acid — all in active forms to help with energy metabolism, focus, mood regulation, and healthy growth.
Minerals: Iron (2 mg), iodine, magnesium, zinc, copper, manganese, calcium — foundational minerals that support thyroid health, bone strength, immunity, and oxygen transport.
Extras:
Probiotic (Lactobacillus acidophilus, 200M CFU): Helps balance gut health and supports digestion and immune resilience.
Lutein + Zeaxanthin: Protect eye health and support healthy visual development in growing kids.
Citrus bioflavonoids: Work synergistically with vitamin C for antioxidant and immune support.
Inositol + PABA: Support healthy mood balance, focus, and nervous system function.
Clean Label: Sweetened with xylitol and stevia, flavored naturally. No gluten, dairy, soy, or GMOs.
Form: Chewable tablet. Ages 4+.
✅ Why it stands out: Unlike many multis, Vesica combines methylation support + probiotics + vision nutrients + minerals in one formula. It’s both comprehensive and clean — covering brain, gut, immune, and eye health in addition to methylation.
❌Cons: It would be cool if it had K2, but many people supplement this separately, so it’s not uncommon for multi’s to exclude it.
💰 Cost at the time this article was written: You get 60 servings and their current price is $44 for the cost of $.73 per serving, before shipping.
Seeking Health – Kids Optimal Multivitamin Chewable
Folate: 64% DV from a mix of L-5-MTHF (Quatrefolic®) and folinic acid (methyl-free).
B12: 833% DV from a blend of methylcobalamin + adenosylcobalamin (MecobalActive®).
Other B’s: All active forms.
Minerals: Comprehensive
Iodine
Magnesium (a small amount)
Selenium
Copper
Manganese
Molebdenum
Iron
Chromium: Supports healthy blood sugar levels which may aid in mood regulation.
Extras:
Zeaxanthin
Lutein
Vitamins C & E, vitamin K2 (MK-7)
Boron
Clean Label: Sugar-free chewables; third-party tested.
Form: Chewable.
✅Pros: Broad active-B profile plus chelated minerals and vision/antioxidant extras; notable inclusion of K2 and iron.
❌Cons: It has a lower amount of methylfolate (64% DV), so that should be noted. Additionally, is has a higher amount of b12 which some children may find overstimulating. The b12 is two forms (methyl and adenosyl b12), but we aren’t given the % of the split.
💰 Cost at the time this article was written: You get 30 servings for $30 (before any potential shipping) for the cost of $1.00 per serving. This is on the more expensive side.
MaryRuth’s – Kids Methyl Multivitamin Gummies
Folate: 50% DV of 5-MTHF methylfolate in one serving.
B12: 100% DV Methylcobalamin in one serving.
Other B’s: Standard forms, not all coenzyme active.
Minerals: Limited mineral profile (basic support only).
Extras: Vegan, sugar-free, natural flavors.
Clean Label: Gluten-free, organic, dairy-free, soy-free, non-GMO.
Form: Gummies.
✅ Pros: A kid-friendly gummy option with methylated folate and B12.
❌Cons: Lighter on minerals and less comprehensive than other methylated multis. For those that want higher levels of methylfolate because they know their child doesn’t overmethylate/get overstimulated, it only has 50% DV of methylfolate.
💰 Cost at the time this article was written: You get 30 servings and their current price is ~$23 for the cost of $.77 per serving, before shipping.
SmartyPants – Kids Multivitamin Gummies
Folate: 63% DV from 5-MTHF methylfolate.
B12: 75% DV Methylcobalamin.
Other B’s: Mix of active and standard forms, including P5P for B6.
Minerals: Light coverage (iodine, zinc).
Extras: Omega-3 ALA (flaxseed oil), probiotic (Bacillus subtilis DE111®), a small amount of choline, vitamin K2.
Clean Label: Organic, non-GMO, natural colors, but contains added sugars.
Form: Gummies.
✅ Pros: A tasty gummy with methylated folate and B12 plus extras like probiotics and omega-3.
❌Cons: Has lower amount of methylated vitamins (63% folate and 75% methyl b12). Lighter on minerals and does contain sugar.
💰 Cost at the time this article was written: You get 30 servings and their current price is ~$30 for the cost of $1.00 per serving, before shipping.
Hiya Kids Daily Chewable
Folate: 50% DV from 5-MTHF active folate and from organic quinoa sprouts.
B12: 83% DV from Methylcobalamin and from organic quinoa sprouts.
Other B’s: Mix of active forms.
Minerals: Calcium, iodine, zinc, selenium, manganese.
Extras: Fruit and vegetable blend, K2.
Clean Label: Uses monk fruit. Vegan, no sugar, no artificial dyes.
Form: Chewable tablet.
✅ Very clean formula, but less comprehensive coverage compared to Vesica. Comes in glass bottle.
❌Cons: Lower amount of folate and b12 compared to other options. Appears to subscription only at the time of this writing, so that may or may not be ideal for you.
💰 Cost at the time this article was written: You get 30 servings and their current price is ~$30 for the cost of $1.00 per serving, before shipping.
Methyl-Life – Chewable Methylated Multivitamin for MTHFR/Pregnancy/Children
Warning: this supplement has a very high amount of b12, so I don’t really recommend it in use for kids. That said, I like hydroxycobalamin for those that are sensitive to methyl b12, and it gives us a good opportunity to discuss this point, so we’ve included it here.
Folate: 350% DV from 5-MTHF methylfolate.
B12: 13,875% from hydroxycobalamin acetate.
Other B’s: Active forms.
Minerals: iodide, zinc, selenium, manganese, molybdenum
Extras: Artichoke leaf, Citocoline, Ubiquinol, phosphatidylserine, milk thistle, panthethine, PABA, benfotiamine, NADH, K2
Clean Label: Xylitol.
Form: Chewable.
✅ Pros: It has a lot of good ingredients including hydroxycobalamin, which is good for some people. You can learn more about hydroxycobalamin vs other b12 versions here.
❌Cons: Methyl-Life’s Kid’s Chewable Multivitamin has a lot of extras, some of which your child may not tolerate well. It also has a fairly high amount of selenium. Selenium is good, but I personally avoid getting too much. It also is a VERY high dosage for kids if you take the recommended 4 tablets.
💰 Cost at the time this article was written: You get 30 servings and their current price is ~$42 for the cost of $1.40 per serving, before shipping.
Side-by-Side Comparisons
| Product | Servings | Price (USD) | Cost / Serving | Notes |
|---|---|---|---|---|
| Vesica Wellness – Children’s Methyl Multi Vite Chewable | 60 | $44.00 | $0.73 | Before shipping |
| Seeking Health – Kids Optimal Multivitamin Chewable | 30 | $30.00 | $1.00 | Before shipping |
| MaryRuth’s – Kids Methyl Multivitamin Gummies | 30 | ~$23.00 | $0.77 | Approximate price; before shipping |
| SmartyPants – Kids Multivitamin Gummies | 30 | ~$30.00 | $1.00 | Approximate price; before shipping |
| Hiya – Kids Daily Chewable | 30 | ~$30.00 | $1.00 | Approximate price; before shipping |
| Methyl-Life – Chewable Methylated Multivitamin | 30 | ~$42.00 | $1.40 | Approximate price; before shipping |
| Prices and per-serving costs are taken from the article at the time of writing and may change over time. | ||||
| Feature | Vesica Wellness | Seeking Health | Methyl-Life | SmartyPants | Hiya | MaryRuth’s |
|---|---|---|---|---|---|---|
| Folate | 5-MTHF (Magnafolate® C) | 5-MTHF + Folinic | 5-MTHF | 5-MTHF | 5-MTHF | 5-MTHF |
| B12 | Methylcobalamin | Methyl + Adenosyl | Methyl | Methylcobalamin | Methyl | Methyl |
| Other B’s | All active | All active | Active | Mix of active + standard | Active | Standard |
| Minerals | Full + iron | Full + iron | Limited | Light (iodine, zinc) | Limited | Limited |
| Extras | Probiotic, lutein, zeaxanthin, bioflavonoids, inositol | L-carnitine, CoQ10, lutein, zeaxanthin, boron, K2 | Few extras | Omega-3s, probiotic, choline, vitamin K2 | Probiotic blend | Vegan, sugar-free, natural flavors |
| Sweetener | Xylitol + stevia | Xylitol + stevia | Xylitol + stevia | Organic cane sugar + tapioca syrup | Monk fruit + xylitol | Sugar-free |
| Clean Label | ✅ | ✅ | ✅ | ❌ (added sugars) | ✅ | ✅ |
| Age Range | 4+ | 4+ | 4+ | 4+ | 2+ | 4+ |
Which One Should You Choose?
-
If you want the most complete all-in-one methylated multi for kids →
Vesica Wellness Children’s Methyl Multi Vite Chewable.
...or, if you prefer powder, they also have that, here: Kid’s Methyl Multi Powder. - If you want something a little less potent for folate and potentially overstimulating for B12, and are okay without probiotics or iron → Seeking Health Kids Optimal.
- If you want a simple methylation chewable → Methyl-Life.
- If your child prefers gummies → MaryRuth’s.
- If you want ultra-clean but basic coverage → Hiya.
Final Thoughts
Choosing a multivitamin isn’t just about filling gaps — it’s about choosing forms your child’s body can actually use. For kids with MTHFR or methylation needs, methylated vitamins are essential.
Among the leading options, Vesica Wellness Children’s Methyl Multi Vite Chewable offers the best combination of active methylation support, extra gut and eye health nutrients, clean formulation, and comprehensive mineral coverage. It’s not just a vitamin — it’s whole-child support in a simple daily chewable.